As an everyday thong wearer, I never really have had an issue wearing thongs to work. I wear a suit to work everyday so unless my pant rip, it is highly unlikely that a slip will happen. One of my female co-workers knows that I wear thongs, but outside of her no one else does.
The only downside is that I am constantly moving and not doing a lot of sitting. So it can get a little uncomfortable if my underwear shifts. But overall, I enjoy wearing thongs daily.